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WorksheetsPharm: Antibiotics
Total questions: 59
Worksheet time: 37mins
Penicillins MOA
Inhibits protein synthesis
Inhibits cell wall synthesis
Inhibits folate production
Inhibits nucleic acid synthesis
Penicillin indications
G+
G+ anaerobes
Broad spectrum
G-
Penicillins common side effects
Nephrotixicity
N/V/D
Ataxia
Abdominal pain
Hepatotoxicity
Penicillins serious side effects
Seizures
C Diff
Red man syndrome
Steven’s-Johnson syndrome
Hepatotoxicity
Allergic reaction to penicillins
Rash
Possible anaphylaxis
Inflammatory conditions
Nausea
Fever
If allergic to one penicillin,
Allergic to amoxicillin
Allergic to ampicillin
Allergic to all penicillins
Allergic to aminoglycosides
How many generations of penicillins are there
2
3
4
5
Cephalosporins MOA
Inhibits protein synthesis
Inhibits cell wall synthesis
Inhibits folate production
Inhibits nucleic acid synthesis
Cephalosporins indications
G+
G+ anaerobes
Broad spectrum
G-
Cephalosporins common side effects
Nephrotixicity
N/V/D
Ataxia
Abdominal pain
Hepatotoxicity
Cephalosporins serious side effects
Seizures
C Diff
Red man syndrome
Steven’s-Johnson syndrome
Hepatotoxicity
What to avoid when taking Cephalosporins
Penicillins
Blood thinners
Dairy
Alcohol
If allergic to cephalosporins, likely
Allergic to amoxicillin
Allergic to ampicillin
Allergic to penicillins
Allergic to aminoglycosides
How many generations of cephalosporins are there
2
3
4
5
Examples of cephalosporins
Cefazolin
Ciprofloxacin
Ceftriaxone
Cephalexin
Glycopeptides MOA
Inhibits protein synthesis
Inhibits cell wall synthesis
Inhibits folate production
Inhibits nucleic acid synthesis
Glycopeptides indications
G+
G+ anaerobes
Broad spectrum
G-
Glycopeptides common side effects
Nephrotixicity
N/V
Ataxia
Abdominal pain
If IV phlebitis
Glycopeptides serious side effects
Nephrotoxicity
Ototoxicity
Red man syndrome
Neutropenia
Hepatotoxicity
Glycopeptides are paired with Metronidazole to treat
Yeast infections
UTI’s
Steven’s-Johnson syndrome
C Diff
Aminoglycosides MOA
Inhibits protein synthesis
Inhibits cell wall synthesis
Inhibits folate production
Inhibits nucleic acid synthesis
Aminoglycosides indications
G+
G+ anaerobes
Broad spectrum
G-
Aminoglycosides common side effects
Nephrotixicity
N/V/D
Ataxia
Ototoxicity
Hepatotoxicity
Aminoglycosides serious side effects
Seizures
C Diff
Red man syndrome
None
Hepatotoxicity
Macrolides MOA
Inhibits protein synthesis
Inhibits cell wall synthesis
Inhibits folate production
Inhibits nucleic acid synthesis
Macrolides indications
G+
G+ anaerobes
Broad spectrum
G-
Macrolides common side effects
Nephrotixicity
N/V/D
Ataxia
Abdominal pain
Hepatotoxicity
Macrolides serious side effects
Seizures
C Diff
Red man syndrome
Steven’s-Johnson syndrome
Hepatotoxicity
Macrolides are often the choice for people with allergies to
Lincosamides
Tetracyclines
Sulfonamides
Penicillin
Examples of Macrolides
Erythromycin
Clindamycin
Doxycycline
Azithromycin
Lincosamides MOA
Inhibits protein synthesis
Inhibits cell wall synthesis
Inhibits folate production
Inhibits nucleic acid synthesis
Lincosamides indications
G+
G+ anaerobes
Broad spectrum
G-
Lincosamides common side effects
Nephrotixicity
N/V/D
Ataxia
Abdominal pain
Hepatotoxicity
Lincosamides serious side effects
Hypersensitivity/rash
C Diff
Red man syndrome
Steven’s-Johnson syndrome
Hepatotoxicity
Examples of Lincosamides
Tetracycline
Doxycycline
Clindamycin
Erythromycin
Tetracyclines MOA
Inhibits protein synthesis
Inhibits cell wall synthesis
Inhibits folate production
Inhibits nucleic acid synthesis
Tetracyclines indications
G+
G+ anaerobes
Broad spectrum
G-
Tetracyclines common side effects
Fatigue
N/V/D
Dizziness
Vestibular reactions
Photosensitivity
Tetracyclines serious side effects
Seizures
C Diff
Red man syndrome
Steven’s-Johnson syndrome
Hepatotoxicity
Never use tetracyclines
In adulthood
In childhood
In pregnancy
In old age
Sulfonamides MOA
Inhibits protein synthesis
Inhibits cell wall synthesis
Inhibits folate production
Inhibits nucleic acid synthesis
Sulfonamides indications
G+
G+ anaerobes
Broad spectrum
G-
Sulfonamides common side effects
Nephrotixicity
N/V/D
Photosensitivity
Rash
Hepatotoxicity
Sulfonamides serious side effects
Seizures
C Diff
Red man syndrome
Steven’s-Johnson syndrome
Hepatotoxicity
Examples of sulfonamides
Trimethoprim
Sulfamethoxazole
Antiprotozoal
Bactrim/Septra
Sulfonamides are commonly used for
UTIs
Yeast infections
C Diff
Steven’s-Johnson syndrome
Quinolones/fluoroquinolones MOA
Inhibits protein synthesis
Inhibits cell wall synthesis
Inhibits folate production
Inhibits nucleic acid synthesis
Quinolones/fluoroquinolones indications
G+
G+ anaerobes
Broad spectrum
G-
Quinolones/fluoroquinolones common side effects
Dizziness
N/V/D
Headache
Insomnia
Photosensitivity
Quinolones/fluoroquinolones serious side effects
Seizures
C Diff
Increased intracranial pressure
Steven’s-Johnson syndrome
Hepatotoxicity
Examples of quinolones/fluoroquinolones
Azithromycin
Clindamycin
Levoflaxacin
Ciproflaxacin
Metronidazole MOA
Inhibits protein synthesis
Inhibits cell wall synthesis
Inhibits folate production
Inhibits nucleic acid synthesis
Metronidazole indications
G+
Giardia
C Diff
G-
Metronidazole common side effects
Nephrotixicity
Nausea, anorexia, diarrhea
Unpleasant taste
Abdominal pain, headache, dizziness
Hepatotoxicity
Metronidazole serious side effects
Seizures
C Diff
Red man syndrome
Steven’s-Johnson syndrome
Hepatotoxicity
Metronidazole is an antibiotic plus
Antiprotozoal
Sulfamethoxazole
Amoebicidal
Ciprofloxacin
Examples of penicillins
Amoxicillin
Ampicillin
Methicillin
Cefazolin
Examples of Glycopeptides
Streptomycin
Vancomycin
Gentamicin
Clindamycin
Examples of aminoglycosides
Streptomycin
Vancomycin
Clindamycin
Gentamicin
