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BIOCHEMISTRY PART 2

Total questions: 69

Worksheet time: 35mins

Name
Class
Date
1.

Amylum is a glucose polymer with bonds connecting atom C numbers:

a)

C1-5

b)

C1-4

c)

C1-3

d)

C1-6

e)

C1-2

2.

The synthesis of porphyrin requires which one of the following amino acids?

a)

Glycine

b)

Cystine

c)

Methionine

d)

Glutamic acid

e)

Alanine

3.

Sucrose is a combination of glucose and fructose. The disaccharide is formed as a result of glycoside bond between atom C number:

a)

C1-3

b)

C1-2

c)

C1-6

d)

C1-5

e)

C1-4

4.

The function of lung surfactant is:

a)

To transport the gases into the blood

b)

To increase the affinity to gases to protein in the circulation

c)

To decrease the solubility of the gases in alveoli

d)

To increase the surface tension between gases and lipid

e)

To decrease the surface tension between gases and liquid

5.

Which one of the following ions is the major cation in the erythrocyte?

a)

Zn ion

b)

Ca ion

c)

Na ion

d)

K ion

e)

Mg ion

6.

A newborn is seen by a doctor with the symptoms of diarrhea every time the baby feeds. Laboratory test indicates a congenital deficiency of enterokinase, the enzymes that normally activates which of the following zymogen?

a)

Chymotrypsinogen

b)

Procarboxypeptidase

c)

Trypsinogen

d)

Proelastase

e)

Pepsinogen

7.

Which of the following ions is the major cation in the extracellular fluid?

a)

Mg ion

b)

Ca ion

c)

Na ion

d)

NH4 ion

e)

K ion

8.

The most important solute for the distribution and retention of body water is:

a)

Amino acid

b)

Protein

c)

Urea

d)

Inorganic electrolytes

e)

Glucose

9.

The transportation of CO2 by the blood circulation form the tissue to the lungs is mainly in the form of:

a)

Physical solution in the blood

b)

Carbamino complex with albumin

c)

Carbamino complex with hemoglobin

d)

Bicarbonate

e)

Carbonic acid

10.

Dietary triacylglycerols are absorbed from the intestinal lumen mainly as:

a)

Fatty acid and 2-monoacylglycerol

b)

Fatty acid and glycerol phosphate

c)

Fatty acid and 1,2-diacylglycerol

d)

Fatty acid and glycerol

e)

Fatty acyl-CoA and glycerol

11.

What is the principal factor which controls the location and the amount of fluid in the various compartments of the body?

a)

pH

b)

Osmotic force

c)

The leucocyte concentration

d)

The erythrocyte concentration

e)

Temperature

12.

Which of the following cases of acid-base imbalance is present in patients with morphine poisoning?

a)

Respiratory acidosis

b)

Metabolic alkalosis hypokalemia

c)

Metabolic alkalosis

d)

Metabolic acidosis

e)

Respiratory alkalosis

13.

A medical student becomes extremely anxious the night before a biochemistry examination and begins to hyperventilate uncontrollably. What initial effects does hyperventilation have on the student’s PCO2 and blood pH?

a)

PCO2 increases and pH increases

b)

PCO2 decreases and pH increases

c)

PCO2 increases and pH decreases

d)

PCO2 decreases and pH decreases

e)

No effect

14.

Which of the following enzymes related to digestion is secreted by the small intestine?

a)

Lipase

b)

Carboxypeptidase

c)

Amylase

d)

Aminopeptidase

e)

Cholesterol esterase

15.

Unsaturated fatty acid can turn into saturated fatty acid by adding:

a)

N

b)

H

c)

O

d)

C

e)

S

16.

Which of the following organs serves in regulating the concentrations of H2CO3 in the blood?

a)

Kidney

b)

Lung

c)

Liver

d)

Spleen

e)

Brain

17.

Which of the following organs store an essential emulsifier of lipids?

a)

Liver

b)

Spleen

c)

Stomach

d)

Pancreas

e)

Gall bladder

18.

How would you describe a nucleic acid molecule?

a)

A polymer of nucleosides

b)

One nucleoside bound to one nucleotide

c)

Binding of 2 nucleosides

d)

Binding of 2 nucleotides

e)

A polymer of nucleotides

19.

Transport of oxygen by the blood from the lungs to the tissues is carried out by:

a)

Bicarbonate

b)

Carbonic acid

c)

Albumin

d)

Myoglobin

e)

Hemoglobin

20.

Which of the following enzymes is an intestinal protease?

a)

Rennin

b)

Ptyalin

c)

Myokinase

d)

Trypsin

e)

Transaminase

21.

Which of the following amino acids is required for the synthesis of heme?

a)

Alanine

b)

Prolin

c)

Glutamic acid

d)

Tyrosine

e)

Glycine

22.

The monomer of polypeptide molecule is:

a)

Adenine

b)

Phosphoric acid

c)

Amino acid

d)

Glycerol

e)

Ribose

23.

The number of hydrogen bonds between the two strands of the duplex oligonucleotide illustrated below is: G T C A T C A G T A

a)

14

b)

7

c)

17

d)

12

e)

5

24.

The primary structure of protein is maintained by covalent ‘back bone’ of the polypeptide formed by the specific amino acid sequence, such as:

a)

Sulfide bond and hydrogen bond

b)

Hydrogen bond and van der Waals forces

c)

Peptide bond and sulfide bond

d)

Peptide bond and hydrophobic interaction

e)

Peptide bond and hydrogen bond

25.

The function of pancreas related to digestion is production of:

a)

Sucrase

b)

Trypsin

c)

Lactase

d)

Pepsin

e)

Lipase

26.

Which of the following protease is an exopeptidase?

a)

Chymotrypsin

b)

Enterokinase

c)

Carboxypeptidase

d)

Trypsin

e)

Pepsin

27.

An example of fibrous protein is

a)

Myoglobin

b)

Immunoglobulin

c)

Albumin

d)

Collagen

e)

Hemoglobin

28.

Which of the following acid-base imbalance is present in a patient with bronchial asthma?

a)

Respiratory acidosis

b)

Respiratory alkalosis

c)

Metabolic acidosis

d)

Metabolic alkalosis

e)

Normal acid-base balance

29.

An example of globular protein is

a)

Actin

b)

Albumin

c)

Insulin

d)

Collagen

e)

Elastin

30.

Which one of the following is the function of the gaster related to digestion?

a)

Produces amylase

b)

Produces chymotrypsin

c)

Produces HCl

d)

Produces bile acid

e)

Produces bicarbonate

31.

Amylase is required for the digestion of which one of the following substances?

a)

Glucosan

b)

Fructosan

c)

Lactose

d)

Sucrose

e)

Amylum

32.

The digestion of polysaccharide begins in

a)

Jejenum

b)

Gaster

c)

Duodenum

d)

Mouth

e)

Esophagus

33.

Which of the following organs stores bile acid?

a)

Gall bladder

b)

Liver

c)

Kidney

d)

Spleen

e)

Pancreas

34.

Which one of the following substances functions as energy source?

a)

Adenosine triphosphate

b)

Adenosine monophosphate

c)

Cytidilate monophosphate

d)

Nicotinamide adenine dinucleotide

e)

Flavin adenine dinucleotide

35.

The product of heme catabolism is

a)

Porphobilinogen

b)

Lecithin

c)

Cholesterol

d)

Bile acid

e)

Bilirubin

36.

Bile salt functions as an emulsifier in digestive system because

a)

Has a polar and apolar structure

b)

Is only soluble in fat

c)

It works as a reducer

d)

Is water soluble

e)

Can work as an enzyme

37.

Which of the following amino acids is the smallest one?

a)

Serin

b)

Tryptophan

c)

Proline

d)

Glycine

e)

Alanine

38.

Lipid has amphipathic characteristics. If polar lipid is in a water medium it will be the form of

a)

Liposomes

b)

Bilayer

c)

Emulsion

d)

Micel

e)

Multilayer

39.

What is the function of bile salt related to digestion of the consumed food?

a)

Oxidation

b)

detoxification

c)

Emulsification

d)

Increase solubility

e)

Hydroxylation

40.

Which of the following substances is the precursor of bile acid synthesis?

a)

Lipoprotein

b)

Phospholipid

c)

Glycoprotein

d)

Cholesterol

e)

Heme

41.

The normal pH of the blood is maintained by the presence of buffer systems in the blood. Which of the following buffer systems is the main extracellular buffer?

a)

Hemoglobin buffer system

b)

Inorganic phosphate buffer system

c)

Albumin buffer system

d)

Bicarbonate-carbonic acid buffer system

e)

Lactate buffer system

42.

What is monomer of nucleic acids?

a)

Phosphoric acid

b)

Nucleotide

c)

Nucleoside

d)

Adenine

43.

The function of salivary glands related to digestion is production of

a)

Rennin

b)

enterokinase

c)

Peptidase

d)

Amylase

e)

Cholesterol esterase

44.

Which of the following is a nonessential amino acid?

a)

Phenylalanine

b)

Tryptophan

c)

Valine

d)

Serine

e)

Leucine

45.

The digestion of dissacharides begins in

a)

Mouth

b)

Gaster

c)

Colom

d)

Esophagus

e)

Jejenum

46.

Example of naturally occurring amino acid which is non found in protein molecules is

a)

Phenylalanine

b)

Taurine

c)

Asparagine

d)

Glutamine

e)

Leucine

47.

An example of primary structure level of protein is

a)

Enzyme

b)

Insulin

c)

Albumin

d)

Actine

48.

An infant present with neonatal jaundice. After several weeks the jaundice becomes more exaggerated. The patient has an enzyme deficiency. Which inhibits the conjugation of bilirubin. Which of the following substances is the conjugate group?

a)

Glycine

b)

Acetic acid

c)

Taurine

d)

Glucuronic acid

e)

Sulfate

49.

Which of the following is an essential amino acid?

a)

Aspartic acid

b)

Methionine

c)

Hydroxylysine

d)

Alanine

e)

Tyrosine

50.

DNA can be found in

a)

Nucleus and cell membrane

b)

Nucleus and cytoplasm

c)

Nucleus and mitochondria

d)

Nucleus and lysosomes

e)

Nucleus and golgi’s apparatus

51.

The transportation of O2 by the blood circulation from the lung to the tissues in the body is mainly carried by

a)

Hemoglobin

b)

Albumin

c)

Bicarbonate

d)

Carbonic acid

e)

Myoglobin

52.

Which one of the following lipids is the main component of lung surfactant?

a)

Arachidonic acid

b)

Triacylglycerol

c)

Prostaglandin

d)

Cholesterol

e)

Dipalmitoyl lecithin

53.

Which of the following amino acids contains hydroxyl group?

a)

Methionine

b)

Arginine

c)

Proline

d)

Serine

e)

Glycine

54.

In duplex DNA molecule, hydrogen bonds are found between

a)

Adenine and uracil

b)

Thymine and cytosine

c)

Uracil and thymine

d)

Cytosine and guanine

e)

Adenine and cytosine

55.

Oxidation can damage cell membrane primarily due to

a)

Changing membrane architecture

b)

Change of cell component activity

c)

Disrupting membrane transport system

d)

Forming ionic bonds

e)

Changing polyunsaturated fatty acids

56.

Which of the following enzymes becomes inactivated after entering the gaster?

a)

Ribonuclease

b)

Amylase

c)

Lactase

d)

Trypsin

e)

Lipase

57.

Dehydration is frequently a complication of a disorder, such as

a)

Nephrotic syndrome

b)

Diabetes melitus

c)

Heart disease

d)

Renal failure

58.

Triacyglycerol is predominantly found in

a)

HDL and VLDL

b)

HDL and cylomicron

c)

VLDL and LDL

d)

HDL and LDL

e)

VLDL and chylomicron

59.

A patient with respiratory acidosis will be compensated by

a)

Hyperventilation

b)

Increased sodium reabsorption in renal tubules

c)

Increased bicarbonate reabsorption in renal tubules

d)

Hypoventilation

e)

Decreased bicarbonate reabsorption in renal tubules

60.

An example of quaternary structure level of protein is

a)

Collagen

b)

Hemoglobin

c)

Myoglobin

d)

Actin insulin

61.

Amino acids can be linked to create protein by

a)

Peptide bonds

b)

Glycosidic bonds

c)

Hydrogen bonds

d)

Phosphate bonds

e)

Ester bonds

62.

Which of the following amino acids has no asymmetric carbon?

a)

Cysteine

b)

Histidine

c)

Glutamic acid

d)

Glycine

e)

Lysine

63.

The highest content of element is organic substance by dry weight is…

a)

N

b)

C

c)

H

d)

O

e)

S

64.

NAD+ serves as coenzyme for the enzyme …

a)

Hydrolase

b)

Transferase

c)

Isomerase

d)

Ligase

e)

Oxidoreductase

65.

Enzymes are classified into 6 major groups based on

a)

Size of enzyme molecule

b)

Optimal pH of enzyme activity

c)

Optimal temperature of enzyme activity

d)

Enzyme reaction

e)

Enzyme substrate

66.

Specific activity is calculated as the number of unit enzyme activity per weight (g, mg) of enzyme protein. The value of enzyme specific activity indicates or is a measure of …

a)

Affinity for substrate

b)

Optimum temperature

c)

Optimum pH

d)

Molecular weight

e)

Enzyme purity

67.

FAD is a coenzyme derived from the vitamin

a)

Nicotinic acid

b)

Folic acid

c)

Thiamin

d)

Riboflavin

68.

A plot of substrate concentration against enzyme activity has the shape of …

a)

Straight line

b)

Parabole

c)

Hyperbole

d)

Sigmoid

e)

Belt

69.

The michaelis constant reflects …

a)

Type of enzyme reaction

b)

Structure of substrate molecule

c)

Type of enzyme for substrate

d)

Affinity of enzyme for substrate

e)

Affinity of enzyme for inhibitor

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