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Unit 7 Dogma

Total questions: 153

Worksheet time: 5hrs 6mins

Name
Class
Date
1.
In a strand of DNA, if it contains 20% of Thymine, then how much Guanine would be present?
a)
30%
b)
20%
c)
80%
d)
10%
2.
Which sequence of DNA bases would pair with this partial strand
ATG TGA CAG
a)
ATG TGA CAG
b)
TAC ACT GTC
c)
GTA AGT GAC
d)
CAT TCA CTG
3.
Which of the following best describes a DNA molecule?
a)
double helix
b)
contains ribose
c)
made of amino acids
d)
contains Uracil
4.
Which of the following units are repeatedly joined together to form a strand of DNA?
a)
amino acids
b)
nucleotides
c)
fatty acids
d)
polysaccharides
5.
Which of the following units are repeatedly joined together to form a strand of DNA?
a)
amino acids
b)
nucleotides
c)
fatty acids
d)
polysaccharides
6.
In a molecule of double-stranded DNA, the amount of Adenine present is always equal to the amount of
a)
cytosine
b)
guanine
c)
thymine
d)
uracil
7.
What determines the code, or information, of a DNA molecule?
a)
the shape (structure) of the nitrogen bases
b)
the order (sequence) of the nitrogen bases
c)
the color of the nitrogen bases
d)
the frequency (number) of nitrogen bases
8.
The following picture must be
a)
DNA because it's double stranded
b)
RNA because it's single stranded
c)
DNA because it's single stranded
d)
RNA because it's double stranded
9.
I am a single strand.
a)
DNA
b)
RNA
10.
I include the bases Guanine, Cytosine, Adenine and Thymine.
a)
DNA
b)
RNA
11.
I include the bases Guanine, Cytosine, Adenine and Uracil .
a)
DNA
b)
RNA
12.
I travel outside of the nucleus.
a)
DNA
b)
RNA
13.
Guanine goes with __________
a)
adnine
b)
cytosine
c)
guanine
d)
thymine
14.
I have the sugar ribose.
a)
DNA
b)
RNA
15.
I have the sugar dioxyribose.
a)
DNA
b)
RNA
16.
There 3 types of 
a)
DNA
b)
RNA
17.
In DNA the sides of the double helix is made of 
a)
deoxyribose  and phosphates
b)
adenine and guanine
c)
thymine and cytosines
18.
The sugar in DNA is ____________________.
a)
deoxyribose
b)
ribose
19.
The sugar in RNA is ____________________.
a)
deoxyribose
b)
ribose
20.
What is a mutation?
a)
a change in DNA
b)
a person who is bitten by a radioactive spider
21.
The results of mutation are 
a)
can be bad.
b)
can be good. 
c)
cannot show.
d)
 can be good, bad or neutral. 
22.
In RNA, adenine goes with __________.
a)
adnine
b)
cytosine
c)
thymine
d)
uracil
23.
Why does DNA stay in the nueclus?
a)
To protect it from becoming damaged.
b)
It is lazy. 
c)
It is grounded. 
d)
It cannot move. 
24.

Which of the following is a type of RNA?

a)

mRNA

b)

tRNA

c)

rRNA

d)

All of these are types of RNA

25.

RNA and DNA are composed of different sugars. Which of the following statements are true?

a)

RNA uses ribose and DNA uses deoxyribose.

b)

RNA uses deoxyribose and DNA uses ribose.

c)

DNA and RNA both use ribose sugars.

d)

DNA and RNA both use deoxyribose sugars.

26.
Where does transcription take place?
a)
nucleus
b)
cytoplasm
c)
ribosome
27.
What is occurring in this picture?
a)
Translation
b)
Replication
c)
Translocation
d)
Transcription
28.
What does mRNA do?
a)
provides information from DNA to ribosomes
b)
transfers amino acids to the ribosomes
c)
makes up ribosomes
d)
builds proteins
29.

Using this DNA sequence ATA CGA GGA TTT, what is the complementary RNA sequence will be

a)

UAU GCU CCU AAA

b)

UAU GCU CCU TTT

c)

TAT GCT CCT AAA

d)

TAT GCT CCT TTT

30.

Through the process of transcription, DNA makes a complimentary strand of

a)

DNA

b)

RNA

c)

CNA

d)

PLB

31.
RNA has how many strands?
a)
one
b)
two
32.

Name the 3 types of RNA

a)

mRNA

dRNA

rRNA

b)

mRNA

tRNA

rRNA

c)

mRNA

tRNA

cRNA

d)

mRNA

dRNA

tRNA

33.

What does a promoter do?

a)

binds RNA polymerase for transcription

b)

binds DNA polymerase for replication

c)

binds the operator

d)

binds the repressor

34.

What does RNA stand for?

a)

Ribonucleic acid

b)

Ricenucleic acid

c)

Ribouncenucleic acid

d)

Rinucleic acid

35.

What are the 4 RNA nitrogen bases?

a)

adenine, thymine, cytoplasm, and guanine

b)

adenine, thymine cytosine, and guanine

c)

adenine, uracil, cytoplasm, and guanine

d)

adenine, uracil, cytosine, and guanine

36.

What is the monomer of RNA?

a)

amino acids

b)

nucleotides

c)

fatty acids

d)

polysaccharides

37.

DNA contains the template to make RNA

a)

True

b)

False

38.

What is the process that makes a complementary mRNA strand from a DNA strand?

a)

protein synthesis

b)

transcription

c)

translation

d)

DNA Polymerase

39.
Where does transcription take place?
a)
nucleus
b)
cytoplasm
c)
ribosome
40.
What does mRNA do?
a)
provides information from DNA to ribosomes
b)
transfers amino acids to the ribosomes
c)
makes up ribosomes
d)
builds proteins
41.

Using this DNA sequence AAA TTT, what is the complementary RNA sequence will be

a)

UUU AAA

b)

AAA UUU

42.
What part of a nucleotide accounts for the genetic variation between individuals?
a)
phosphate
b)
nitrogenous base
c)
deoxyribose
d)
sugar
43.
Which phrase best describes translation?
a)
converts mRNA into a polypeptide
b)
catalyzes bonds between amino acids
c)
produces RNA from DNA molecules
d)
recycles tRNA molecules for reuse
44.

True or False: RNA uses deoxyribose sugar.

a)

True

b)

False

45.

Through the process of transcription, DNA makes a complimentary strand of

a)

DNA

b)

RNA

c)

CNA

d)

PLB

46.

After transcription mRNA goes from the nucleus to the _________.

a)

Ribosome

b)

Mitochondria

c)

Endoplasmic Reticulum

d)

Vacuoles

47.

The first step of protein synthesis is.....

a)

replication

b)

mitosis

c)

translation

d)

transcription

48.

Which Nucleic Acids can be found in the nucleus?

a)

DNA only

b)

DNA & RNA

c)

RNA only

d)

enzymes only

49.
Which process is shown?
a)
diffusion
b)
repiration
c)
recombination
d)
translation
50.
Which of the following is the blueprint for the production of RNA within a cell?
a)
DNA
b)
protein
c)
ATO
d)
carbohydrate
51.
The DNA sequence ATCAGCGCTGGC is part of a gene. How many amino acids are coded for by this message?
a)
4
b)
8
c)
12
d)
20
52.
What is the function of DNA helicase?
a)
Attach new nucleotides
b)
To unzip the strands of DNA
c)
Remove nucleotides
d)
To perform crossing over
53.
Which RNA bases would pair with TACGAA in transcription? 
a)
AUGCUU
b)
ATGCTT
c)
GCATCC
d)
GCAUCC
54.
Where does transcription take place?
a)
nucleus
b)
cytoplasm
c)
ribosome
55.
Which of these bases does not exist in RNA?
a)
C
b)
T
c)
U
d)
A
56.
DNA codes for...
a)
cholesterol
b)
proteins
c)
fatty acids
d)
a sandwich
57.
Which process is used to copy DNA in the nucleus?
a)
replication
b)
transcription
c)
translation
58.

DNA contains the template to make RNA

a)

True

b)

False

59.

What enzyme does transcription use?

a)

DNA polymerase

b)

ligase

c)

RNA polymerase

d)

helicase

60.

Which RNA forms part of the ribosomes?

a)

tRNA

b)

mRNA

c)

rRNA

61.

Which RNA carries the message?

a)

mRNA

b)

rRNA

c)

tRNA

62.

Which RNA brings amino acids?

a)

rRNA

b)

tRNA

c)

mRNA

63.

The goal of transcription is to make RNA.

a)

True

b)

False

64.
A triplet of mRNA is called a
a)
codon
b)
anticodon
c)
amino acid
d)
peptide bond
65.

RNA A pairs with?

a)

g

b)

4

c)

u

d)

t

66.
What does this picture represent?
a)
amino acid
b)
base pairing
c)
nucleotide
d)
the DNA molecule
67.
I include the bases guanine, cytosine, and adenine.
a)
DNA
b)
RNA
c)
Both DNA and RNA
68.
How many nucleotides make a codon?
a)
1
b)
2
c)
3
d)
6
69.

Transcribe the following DNA strand: CTG AAT

a)

GAC TTA

b)

CTG AAT

c)

GAC UUA

d)

CUG AAU

70.

Which of these is not an aspect of the central dogma of biology?

a)

DNA and RNA control protein synthesis

b)

DNA codes for RNA

c)

DNA and RNA are in living things

d)

genetic material is found in protein

71.

What is synthesized to pass the DNA code to the ribosome?

a)

polymerase

b)

messenger RNA

c)

ligase

d)

ribosome

72.

A process called ____ uses the code carried by messenger RNA for protein synthesis.

a)

translation

b)

transcription

c)

unwinding

d)

elongation

73.

Which substance shown here, binds to the site where messenger RNA will be synthesized?

a)

RNA polymerase

b)

template DNA strand

c)

nucleotide

d)

adenine

74.

How many nucleotides make up a codon?

a)

1

b)

3

c)

5

d)

15

75.

How many codons: AAU GCG AUG

a)

9

b)

1

c)

3

d)

15

76.

How many nucleotides? AAU GCG AUG

a)

9

b)

3

c)

1

d)

15

77.
ATCAGTGAT A codon is a sequence of three nucleotides that code for an amino acid. If the DNA sequence shown here goes through transcription and translation, how many amino acids will result from this sequence?
a)
5
b)
4
c)
2
d)
3
78.

What is the order for Protein Synthesis?

a)

Transcription -> Translation -> Protein

b)

Translation - > Transcription -> Protein

c)

Protein -> Transcription -> Translation

d)

Translation -> Protein -> Transcription

79.
Which Seq could be found in RNA?
a)
ACCTGT
b)
CGCATT
c)
AUGCUU
80.
Which shows the correct complementary base pairing for DNA?
a)
C-A, T-G
b)
A-G, C-T
c)
C-G, U-A
d)
T-A, G-C
81.
Which sequence of DNA bases would pair with this partial strand
ATG TGA CAG
a)
ATG TGA CAG
b)
TAC ACT GTC
c)
GTA AGT GAC
d)
CAT TCA CTG
82.
Genes are found on...
a)
chromosomes
b)
alleles
c)
proteins
d)
anthers
83.
Adenine bonds with ______________.
a)
Guanine
b)
Thymine
c)
Cytosine
d)
Adenine
84.
Guanine bonds with ______________.
a)
Adenine
b)
Guanine
c)
Cytosine
d)
Thymine
85.
Which 2 molecules forms the sides (backbone) of the DNA ladder?
a)
deoxyribose and adenine
b)
deoxyribose and a hydrogen bond
c)
sugar and the nucleus
d)
deoxyribose (sugar) and phosphate
86.
What bonds the nitrogen bases in the center of the DNA strand?
a)
Covalent Bonds
b)
Ionic Bonds
c)
Hydrogen Bonds
d)
Metallic Bonds
87.
Which sequence of DNA bases would pair with this partial strand
ATG TGA CAG
a)
ATG TGA CAG
b)
TAC ACT GTC
c)
GTA AGT GAC
d)
CAT TCA CTG
88.
In a sample of DNA, 20 percent is Adenine. What are the percentages of the other bases?
a)
Thymine - 30 percent, Cytosine 25 percent, Guanine 25 percent
b)
Cytosine - 20 percent, Thymine - 30 percent, Guanine 25 percent
c)
Thymine - 20 percent, Cytosine 30 percent, Guanine 30 percent
d)
Thymine - 30 percent, Cytosine 30 percent, Guanine 20 percent
89.
A change in the genetic code = ____
a)
trait
b)
genotype
c)
phenotype
d)
mutation
90.
Why is the order of amino acids so important?
a)
The order of amino acids dictates what shape the protein will fold into.
b)
It is not important. The protein folding chamber will force the protein to fold into the correct shape.
91.
This nucleic acid is single stranded
a)
DNA
b)
RNA
c)
Both
92.
DNA and RNA are macromolecules in the category of
a)
Proteins
b)
Lipids
c)
Nucleic Acids
d)
Carbohydrates
93.
brings amino acids to ribosomes, where they are joined together to form proteins
a)
transfer RNA (tRNA)
b)
Central Dogma of Molecular Biology
c)
messenger RNA (mRNA)
d)
Chargaff’s Rules
94.
helps form ribosomes, where proteins are assembled
a)
Central Dogma of Molecular Biology
b)
messenger RNA (mRNA
c)
ribosomal RNA (rRNA)
d)
Chargaff’s Rules
95.
copies the genetic instructions from DNA in the nucleus, and carries them to the cytoplasm
a)
transfer RNA (tRNA)
b)
ribosomal RNA (rRNA)
c)
messenger RNA (mRNA)
d)
codon
96.
consists of the sequence of nitrogen bases—A, C, G, T (or U)—in a polynucleotide chain
a)
codon
b)
genetic code
c)
transcription
d)
Central Dogma of Molecular Biology
97.
letters are combined in groups of three to form code “words
a)
codon
b)
transcription
c)
Central Dogma of Molecular Biology
d)
messenger RNA (mRNA)
98.
second part of the central dogma of molecular biology: RNA → Protein, process in which the genetic code in mRNA is read to make a protein
a)
transcription
b)
translation
c)
protein synthesis
d)
promoter
99.
process in which cells make proteins
a)
protein synthesis
b)
translation
c)
transfer RNA (tRNA)
d)
ribosomal RNA (rRNA)
100.
beginning of transcription, occurs when the enzyme RNA polymerase binds to a region of a gene
a)
promoter
b)
translation
c)
protein synthesis
d)
transcription
101.
occur in cells of the body, mutations may have little effect on the organism because they are confined to just one cell and its daughter cells, cannot be passed onto offspring.
a)
frameshift mutation
b)
somatic mutation
c)
mutagen
d)
chromosomal alteration
102.
deletion or insertion of one or more nucleotides that changes the reading frame of the base sequence
a)
somatic mutation
b)
frameshift mutation
c)
mutagen
d)
chromosomal alteration
103.
change in the sequence of bases in DNA or RNA
a)
mutagen
b)
mutation
c)
chromosomal alteration
d)
point mutation
104.
disease caused by a mutation in one or a few genes
a)
genetic disorder
b)
mutagen
c)
frameshift mutation
d)
somatic mutation
105.

Which of the following are true regarding TRANSLATION? (mark all that apply)

a)

Occurs in the nucleus

b)

Occurs in the cytoplasm

c)

RNA polymerase is an enzyme used.

d)

DNA polymerase is an enzyme

e)

Transfer RNA is involved in the process

106.

Which of the following enzymes is needed for Transcription?

a)

Helicase

b)

DNA Polymeras

c)

RNA Polymerase

d)

Ligase

e)

Topoisomerase

107.

During TRANSCRIPTION, as the DNA is being read which nucleotides are being used to build the RNA? (mark all that apply)

a)

Adenine

b)

Thymine

c)

Cytosine

d)

Guanine

e)

Uracil

108.

Given the mRNA sequence - 3' AUG CAU GGU.5'. What is the original DNA template strand?

a)

5' TAC GTA CCA 3'

b)

5' UAC GUA CGA 3'

c)

3' UAC GUA CGA 5''

d)

3' TAC GTA CGA 5'

109.

Given the DNA template sequence of 3' TAC GTT ACT 5'. What is the corresponding mRNA strand?

a)

5'AUG CAA UGA 3'

b)

3' ATG CAA TGA 5'

c)

3'AUG CAA UGA 5'

d)

5' ATG CAA TGA 3'

110.

Which of the following steps is NOT part of TRANSCRIPTION in eukaryotes?

a)

Initiation

b)

Elongation

c)

Termination

d)

Transformation

111.

What information is available from the table? (mark all that apply)

a)

mRNA

b)

tRNA

c)

Amino acids

d)

Start anticodon

e)

Stop codon

112.

Which mutation will cause translation to stop?

a)

Mutations 1 and 3 only

b)

Mutation 1 only

c)

Mutation 2 only

d)

Muations 1, 2, 3

113.

Mutations can leave to evolutionary change.

a)

True

b)

False

114.

Mutations can be spontaneous.

a)

True

b)

False

115.

Which of the following is not a type of mutation?

a)

Substitution

b)

Insertion

c)

Prescription

d)

Deletion

116.

THEBIGFATREDCATSAT is the normal message, what type of mutation is this: ZHEBIGFATREDCATSAT

a)

Insertion

b)

Deletion

c)

Substitution

117.

THEBIGFATREDCATSAT is normal, what would this be:

THESBIGFATREDCATSAT

a)

Substitution

b)

Insertion

c)

Deletion

118.

THEBIGFATREDCATSAT is normal, what is this:

THEBIGFATREDATSAT

a)

Substitution

b)

Insertion

c)

Deletion

119.

During TRANSCRIPTION, which molecules and examples could be found? (mark all that apply)

a)

Triplet : TAC

b)

Codon: TAC

c)

Anticodon: UAC

d)

Triplet : AUG

e)

Codon : AUG

120.

What is the purpose of the process of translation and where does it occur?

a)

to synthesize amino acids in the nucleus

b)

to produce a specific sequence of amino acids in the ribosome

c)

to replicate the DNA of an organism in the ribosome

121.

Where are proteins made?

a)

nucleus

b)

mitochondria

c)

ribosomes

122.

What is the job of messenger RNA?

a)

to transfer amino acids

b)

to assemble the protein

c)

to carry genetic information

123.

What is the job of tRNA?

a)

assembles amino acids

b)

transfers the message from the genetic code

c)

transfers the amino acids to the ribosome

124.
Which process is shown?
a)
diffusion
b)
repiration
c)
recombination
d)
translation
125.
The DNA sequence ATCAGCGCTGGC is part of a gene. How many amino acids are coded for by this message?
a)
4
b)
8
c)
12
d)
20
126.
Where does transcription take place?
a)
nucleus
b)
ribosome
c)
cytoplasm
d)
smooth ER
127.
DNA sequence is ACAGTGC. How would this be coded on mRNA?
a)
TGTCACG
b)
UGUCACG
c)
GUGACAU
d)
CACUGUA
128.
Which of the following is incorrect regarding RNA?
a)
RNA contains uracil
b)
RNA can only be found inside the nucleus
c)
RNA is single stranded
d)
RNA contains genetic information
129.
Which of the following sequences of processes correctly reflects the central dogma?
a)
protein synthesis, transcription, translation
b)
protein synthesis, translation, transcription
c)
transcription, translation, protein synthesis
d)
translation, transcription, protein synthesis
130.
In analyzing the number of different bases in a DNA sample, which result would be consistent with the base-pairing rules?
a)
A = G
b)
A + G = C + T
c)
A + T = G + G
d)
A = C
131.

Which of the following would be a description of a mutation?

a)

the creation of RNA using DNA as a template

b)

producing 2 identical strands of DNA from a parent molecule

c)

an unexpected change in the order of nucleotides on a DNA strand

d)

the creation of a protein by reading RNA codons

132.
brings amino acids to ribosomes, where they are joined together to form proteins
a)
transfer RNA (tRNA)
b)
Central Dogma of Molecular Biology
c)
messenger RNA (mRNA)
d)
Chargaff’s Rules
133.
helps form ribosomes, where proteins are assembled
a)
Central Dogma of Molecular Biology
b)
messenger RNA (mRNA
c)
ribosomal RNA (rRNA)
d)
Chargaff’s Rules
134.
copies the genetic instructions from DNA in the nucleus, and carries them to the cytoplasm
a)
transfer RNA (tRNA)
b)
ribosomal RNA (rRNA)
c)
messenger RNA (mRNA)
d)
codon
135.
within each species, concentration of adenine was always about the same as the concentration of thymine, same was true of the concentrations of guanine and cytosine
a)
Central Dogma of Molecular Biology
b)
messenger RNA (mRNA)
c)
Chargaff’s Rules
d)
genetic code
136.
consists of the sequence of nitrogen bases—A, C, G, T (or U)—in a polynucleotide chain
a)
codon
b)
genetic code
c)
transcription
d)
Central Dogma of Molecular Biology
137.
letters are combined in groups of three to form code “words
a)
codon
b)
transcription
c)
Central Dogma of Molecular Biology
d)
messenger RNA (mRNA)
138.
first part of the central dogma of molecular biology: DNA → RNA. It is the transfer of genetic instructions in DNA to mRNA. During transcription, a strand of mRNA is made that is complementary to a strand of DNA
a)
transcription
b)
translation
c)
protein synthesis
139.
second part of the central dogma of molecular biology: RNA → Protein, process in which the genetic code in mRNA is read to make a protein
a)
transcription
b)
translation
c)
protein synthesis
d)
promoter
140.
process in which cells make proteins
a)
protein synthesis
b)
translation
c)
transfer RNA (tRNA)
d)
ribosomal RNA (rRNA)
141.
beginning of transcription, occurs when the enzyme RNA polymerase binds to a region of a gene
a)
promoter
b)
translation
c)
protein synthesis
d)
transcription
142.
deletion or insertion of one or more nucleotides that changes the reading frame of the base sequence
a)
somatic mutation
b)
frameshift mutation
c)
mutagen
d)
chromosomal alteration
143.
Anything in the environment that can cause a mutation
a)
frameshift mutation
b)
chromosomal alteration
c)
mutation
d)
mutagen
144.
mutations that change chromosome structure, occur when a section of a chromosome breaks off and rejoins incorrectly or does not rejoin at all
a)
chromosomal alteration
b)
mutation
c)
genetic disorder
d)
germline mutation
145.
change in the sequence of bases in DNA or RNA
a)
mutagen
b)
mutation
c)
chromosomal alteration
d)
point mutation
146.
disease caused by a mutation in one or a few genes
a)
genetic disorder
b)
mutagen
c)
frameshift mutation
d)
somatic mutation
147.

1) One nucleotide is accidentally put in place instead of another.

2) Changes one codon

a)

substitutions

b)

Frameshifts

c)

Missense

d)

Nonsense

148.

Which possible effect of substitution is being described:

Change has no effect. It usually happens if the new codon codes for the same amino acid.

a)

silent

b)

missense

c)

nonsense

d)

frameshifts

149.

Which possible effect of substitution is being described:

Forms a poorly functioning or misfunctioning protein.

a)

silent

b)

missense

c)

nonsense

d)

frameshifts

150.

Which possible effect of substitution is being described:

Does not form a functional protein. Often caused by an early stop codon.

a)

silent

b)

missense

c)

nonsense

d)

frameshifts

151.

Which possible effect of substitution is being described:

Caused by an insertion or deletion of nucleotides.

Changes the reading frame.

Every amino acid after the insertion or deletion will be wrong.

a)

silent

b)

missense

c)

nonsense

d)

frameshifts

152.

Which class of mutation is being described:

Affects one specific gene.

Change in the nucleotide sequence of a single gene.

May only involve one nucleotide or several.

a)

Large Scale (Chromosomal)

b)

Small Scale (Gene Mutations)

153.

Which class of mutation is being described:

Affects many genes.

Can involve duplications, deletions, and movement of whole chromosomes.

a)

Large Scale (Chromosomal)

b)

Small Scale (Gene Mutations)

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